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Proteasome Inhibitors in Cancer Therapy von Julian Adams (2004, Gebundene Ausgabe)

About this product

About this product

Produktinformation

A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome inhibitors in cancer to a review of current clinical trials underway. The discussion of rationales for testing proteasome inhibitors in cancer models covers the role of the proteasome in NF-kB activation, the combining of conventional chemotherapy and radiation with proteasome inhibition, notably PS-341, new proteasome methods of inhibiting viral maturation, and the role of protesome inhibition in the treatment of AIDS. The authors also document the development of bortezomib (Velcade(TM)) in Phase I clinical trials and in a multicentered Phase II clinical trials in patients with relapsed and refractory myeloma.

Produktkennzeichnungen

Herausgeber
Julian Adams
ISBN-10
1588292509
ISBN-13
9781588292506
eBay Product ID (ePID)
68455903

Produkt Hauptmerkmale

Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
340 Seiten
Verlag
Humana Press
Publikationsname
Proteasome Inhibitors in Cancer Therapy
Autor
Julian Adams
Format
Gebundene Ausgabe
Erscheinungsjahr
2004

Zusätzliche Produkteigenschaften

Hörbuch
No
Inhaltsbeschreibung
Hc Runder Rücken Kaschiert
Item Length
26cm
Item Height
2cm
Item Width
18cm
Item Weight
915g
Buchreihe
Cancer Drug Discovery And Development

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