Cable, Deadpool, Wade Wilson (Villain, First Appearance), Julio Richter (Leaves New Mutants), Amara Aquilla (Cameo), Domino (First Appearance, Joins New Mutants), Tabitha Smith, Xi'an Coy Manh (Cameo), Domino, Skids (Cameo), Magma (Cameo), Nathan Summers, Dani Moonstar (Cameo), Emmanuel Da Costa (Death), Vanessa Carlysle, Cannonball, Roberto Da Costa, Deadpool (Villain, First Appearance), Rictor (Leaves New Mutants), Rusty Collins (Cameo), Adam, Sally Blevins (Cameo), Eve, Gideon (Villain, First Appearance), Vanessa Carlysle (First Appearance, Joins New Mutants), Boom-Boom, Mirage (Cameo), Wade Wilson, Sam Guthrie, Gideon, Sunspot, Karma (Cameo)
