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Doctor's Best Products are excellent. This one in particular does not give me gastrointestinal issues as do other brands. I believe they get their raw materials from Italy.
Verified purchase: Yes | Condition: New
SAM-e has changed my life. It has 100% resolved my treatment-resistant depression with the only side-effects being that with higher doses it causes some occasional anxiety / restlessness or sweating. 1600mg is the sweet spot which is very expensive so I wish the US would make this a prescription that insurance could cover. I noticed if I take a couple of day break, like no dosing on the weekend, the effects are more noticeable. Depending on what's going on you can even just take this as needed over the course of the week as it kicks in very quickly within hours. I've tried many brands with varied results at different doses. This Doctor's Best brand seems great along with other enterically coated blister packaged ones. The ones I purchased here were also 2 years from expiration which many people think makes a difference.Read full review
Verified purchase: Yes | Condition: New
Very good price for this OTC joint pain reliever. Find this helps me get a bit more flexibility from my hip & knee due to arthritis. I take it early AM before I go on my bike ride & it give me the relief I need for that "up & down" movement.
Verified purchase: Yes | Condition: New
I started taking SAMe 400 about a month ago and feel results already. I'm a very active 80-year old and am grateful for the efficacy of this product.
Verified purchase: Yes | Condition: New
Only day 5 but starting to feel positive results already. Hoping that it continues to work for a better outcome.
Verified purchase: Yes | Condition: New
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