The transmembrane electrical potential is a critical aspect of the function of all living cells. In neurons, the dynamics of this potential are of particular importance as the basis for cell signaling. Neurodynamix simulates the dynamic properties of neurons at four levels of neuronal organization and makes the topic of bioelectricity more accessible and less intimidating to students. The modeling system provides a means for students to have access to neurophysiological methods and results by carrying out experiments. Such hands-on simulations deepen students' understanding of electrophysiological concepts and heighten their appreciation of the techniques used to study the electrical properties of cells. The models of Neurodynamix simulate physiological experiments and results dynamically; results are displayed as they are being generated by the models. Based on a highly accessible graphics interface, the computer models encourage active exploration of physiological properties through the manipulation of model parameters while the model experiments are in progress. Section I of the text provides overviews of electrical concepts, the properties of ion channels, resting and action potentials, synaptic interactions, and neuronal circuits. Each of these is followed by descriptions of modeling exercises to be carried out with the NeuroDynamix software. Exercises are designed to illustrate the concepts introduced in the text overviews. Section II provides brief descriptions of the six models incorporated into NeuroDynamix and includes glossaries for variables and parameters. Sections III and IV furnish detailed descriptions of mathematical equations for the models.
Product Identifiers
Publisher
Oxford University Press, Incorporated
ISBN-10
0195082826
ISBN-13
9780195082821
eBay Product ID (ePID)
86630
Product Key Features
Author
w. Otto Friesen, Jonathon A. Friesen
Publication Name
Neurodynamix : Computer Models for Neurophysiology
Format
Trade Paperback
Language
English
Publication Year
1994
Type
Textbook
Number of Pages
224 Pages
Dimensions
Item Length
11.1in
Item Height
0.5in
Item Width
8.5in
Item Weight
24 Oz
Additional Product Features
Lc Classification Number
Qp363.F75 1994
Reviews
Preface: Overview of the System Structure and Use Acknowledgements Section I: Neurophysiology and Modeling Exercises I.1. Introduction to Electricity I.2. Patch Clamp Recording I.3. Origins of the Membrane Resting Potential I.4. Basis of the Nerve Impulse (Action Potential) I.5. Properties of Individual Neurons I.6. Interactions between Neurons I.7. Neuronal Oscillator Circuits Section II: Detailed Guide to the Computer Models II.1. RESISTOR II.2. PATCH II.3. SOMA II.4. AXON II.5. NEURON II.6. CIRCUIT Section III: Guide to the NeuroDynamix Windows III.1. Introduction and Installation III.2. Running NeuroDynamix III.3. Specific Descriptions of NeuroDynamix Windows III.4. Quitting NeuroDynamix Section IV: Numerical Methods Section V: Equations for the Models V.1. RESISTOR V.2. PATCH V.3. SOMA V.4. AXON V.5. NEURON V.6. CIRCUIT Section VI: Bibliography Section VII: Quick Reference Guide to Using the System Appendix
Table of Content
Preface: Overview of the System Structure and UseAcknowledgementsSection I: Neurophysiology and Modeling ExercisesI.1. Introduction to ElectricityI.2. Patch Clamp RecordingI.3. Origins of the Membrane Resting PotentialI.4. Basis of the Nerve Impulse (Action Potential)I.5. Properties of Individual NeuronsI.6. Interactions between NeuronsI.7. Neuronal Oscillator CircuitsSection II: Detailed Guide to the Computer ModelsII.1. RESISTORII.2. PATCHII.3. SOMAII.4. AXONII.5. NEURONII.6. CIRCUITSection III: Guide to the NeuroDynamix WindowsIII.1. Introduction and InstallationIII.2. Running NeuroDynamixIII.3. Specific Descriptions of NeuroDynamix WindowsIII.4. Quitting NeuroDynamixSection IV: Numerical MethodsSection V: Equations for the ModelsV.1. RESISTORV.2. PATCHV.3. SOMAV.4. AXONV.5. NEURONV.6. CIRCUITSection VI: BibliographySection VII: Quick Reference Guide to Using the SystemAppendix
Copyright Date
1994
Topic
Neuroscience, Computer Simulation, Life Sciences / Zoology / General