Two factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases. The quality of the experimental data -- especially nucleic acid sequences -- is satisfactory; however, annotations depend on features inferred from the data rather than measured directly, for instance the identification of genes in genome sequences. It is essential that these inferences are as accurate as possible and this requires human intervention. With the recognition of the importance of accurate database annotation and the requirement for individuals with particular constellations of skills to carry it out, annotators are emerging as specialists within the profession of bioinformatics. This book compiles information about annotation -- its current status, what is required to improve it, what skills must be brought to bear on database curation and hence what is the proper training for annotators. The book should be essential reading for all people working on biological databases, both biologists and computer scientists. It will also be of interest to all users of such databases, including molecular biologists, geneticists, protein chemists, clinicians and drug developers.
Product Identifiers
Publisher
John Wiley & Sons Inc
ISBN-13
9780470856819
eBay Product ID (ePID)
95700514
Product Key Features
Author
Arthur M. Lesk
Publication Name
Database Annotation in Molecular Biology: Principles and Practice
Format
Hardcover
Language
English
Subject
Biology
Publication Year
2004
Type
Textbook
Number of Pages
266 Pages
Dimensions
Item Height
250mm
Item Width
168mm
Item Weight
602g
Additional Product Features
Country/Region of Manufacture
United States
Editor
Arthur M. Lesk
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