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Kratom and Other Mitragynines : The Chemistry and Pharmacology of Opioids from a Non-Opium Source by Robert B. Raffa (2014, Hardcover)

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Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature's only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds--those derived from the plant Mitragyna speciosa . This plant, known as Kratom in Thailand or Biak-Biak in Malaysia, has long been used locally as treatment for pain, fever reduction, diarrhea, and even depression. Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source presents an introduction to the chemical and biological properties of alkaloids isolated from M. speciosa as well as their synthetic analogs. The book covers various topics including phytochemistry, medicinal chemistry, and pharmacology. Current research, analgesic effects, and addiction potential are also discussed. As the first extensive text on the basic science and clinical use of Kratom, the book provides readers with a concise yet comprehensive introduction to nature's "other opioid."

Product Identifiers

Publisher
CRC Press LLC
ISBN-10
1482225182
ISBN-13
9781482225181
eBay Product ID (ePID)
201598991

Product Key Features

Author
Robert B. Raffa
Publication Name
Kratom and Other Mitragynines : the Chemistry and Pharmacology of Opioids from a Non-Opium Source
Format
Hardcover
Language
English
Publication Year
2014
Type
Textbook
Number of Pages
366 Pages

Dimensions

Item Length
9.3in
Item Height
0.9in
Item Width
6.1in
Item Weight
21.7 Oz

Additional Product Features

Lc Classification Number
Rm666.O6
Reviews
"This is a novel foray into the realm of reviews on non-poppy-derived opioids and their pharmacology and ... provides very solid information about the chemistry of the mitragynines...The editor, Robert Raffa, is a widely known expert in the pharmacology of opioid drugs with significant knowledge and respect in the field." --Kenneth E. McCarson, BChE, PhD, University of Kansas Medical Center for Doody's Review Service "This book should be an indispensable single-volume information source for anyone working in the fields of opioid chemistry, pharmacology and toxicology. Some chapters would be of particular interest to ... specialists working in addiction treatment and drug regulation. The book would also be an excellent addition to any library collection specialized in natural products or drugs of abuse." --Journal of Addition Research and Therapy, "This is a novel foray into the realm of reviews on non-poppy-derived opioids and their pharmacology and ... provides very solid information about the chemistry of the mitragynines...The editor, Robert Raffa, is a widely known expert in the pharmacology of opioid drugs with significant knowledge and respect in the field." --Kenneth E. McCarson, BChE, PhD, University of Kansas Medical Center for Doody's Review Service
Table of Content
Why Do Plants Contain Biologically Active Compounds? Oné Pagán Short Overview of Mitragynines; Robert B. Raffa, Jaclyn R. Beckett, Vivek N. Brahmbhatt, Theresa M. Ebinger, Chrisjon A. Fabian, Justin R. Nixon, Steven T. Orlando, Chintan A. Rana, Ali H. Tejani, and Robert J. Tomazic Psychopharmacological Indole Alkaloids from Terrestrial Plants; Allan Patrick G. Macabeo Salvinorin A: Example of a Non-Alkaloidal Bioactive Opioid from a Plant Source; Jordan K. Zjawiony Mitragyna speciosa ( Korth.) Havil; Sasha W. Eisenman Phytochemistry of Mitragyna speciosa ; Vedanjali Gogineni, Francisco Leon, Bonnie A. Avery, Christopher McCurdy and Stephen J. Cutler Chemistry of Mitragynines: A Brief Introduction; Robert B. Raffa Chemistry of Mitragyna Compounds; Mariko Kitajima and Hiromitsu Takayama Medicinal Chemistry Based on Mitragynine; Hiromitsu Takayama and Mariko Kitajima Chemical Structures of Opioids; Robert B. Raffa The Detection of Mitragynine and Its Analogs; Ruri Kikura-Hanajiri The ADME of Mitragynine and Analogs; Annette Cronin, Ines A. Ackerman, and Jochen Beyer Analgesic Effects of Mitragynine and Analogs; Kenjiro Matsumoto and Syunji Horie Non-Analgesic CNS Effects; Jaclyn R. Beckett, Justin R. Nixon, and Ali H. Tejani Other Opioid-Associated Endpoints; Steven T. Orlando and Vivek N. Brahmbhatt The Kratom Experience From Firsthand Reports; Earth Erowid and Fire Erowid The Toxicology of Indole Alkaloids; Jennifer L. Ingram-Ross Opioid-Induced Adverse Effects and Toxicity; Joseph V. Pergolizzi, Jr. Toxicology of Mitragynine and Analogs; Surash Ramanathan and Sharif M. Mansor The Use of Animal Models to Measure Tolerance, Dependence, and Abuse Potential; Scott M. Rawls Kratom: The Epidemiology, Use and Abuse, Addiction Potential, and Legal Status; Zoriah Binti Aziz
Copyright Date
2014
Topic
Pharmacology, Chemistry / General
Lccn
2014-033470
Dewey Decimal
615.7/822
Intended Audience
College Audience
Dewey Edition
23
Illustrated
Yes
Genre
Science, Medical

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5 out of 5 stars
by 1_great_offerJul 01, 2016
Received in excellent condition & well recommended!
This book arrived in great condition & I am very glad to have this book in my possession! It is a wonderful reference for anyone with questions in regards to kratom & the other mitragynines that are available around the world. There is a good amount of medical research material available in this book. Absolutely love it!
Verified purchase: Yes | Condition: New

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Kratom and Other Mitragynines : The Chemistry and Pharmacology of Opioids from a Non-Opium Source by Robert B. Raffa (2014, Hardcover)

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Received in excellent condition & well recommended!

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