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Here's what I know: I took a bottle of this and had no heartburn for about six months after having it 2-6 times almost every week for years. I used Prilosec and a few other treatments and none worked for very long, not even as long as the interim period when I couldn't take it anymore. I told my doctor I was going to take it because I suspected I had h-pylori. She had me tested and the test came back negative. I took it anyway. Six months after taking BIO HPF the heartburn came back with a vengeance, but part of that was taking too much cranberry. I ordered another bottle of BIO HPF and will take it again if decreasing the cranberry doesn't do it for me. I felt no ill effects from taking this supplement. I am chemically sensitive, so that is a plus.
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I had a Dr recommend them to me the 1st time and they worked and then I got it again and took them again recently and it helped immensely.
Verified purchase: No