Quest for Quintana Roo has you helping Yucatan Sam explore dozens of danger-filled chambers that make up the mystical temple of the Mayan god, Quintana Roo. Your mission is to find the keys to open the ceremonial vault and acquire the riches contained therein. The game opens outside the temple; here you must enter a portal to the rooms inside while avoiding poisonous snakes and the moon god's wrath reflecting from the eyes of the temple. Once inside, you will slide down a chute and enter a room.
You can maneuver around each room and fight off snakes, spiders, and mummies by finding and using various tools and weapons such as a gun, magic herbs (for healing bites), flasks of acid, a chisel, and a Geiger counter (for finding items). Score points by killing enemies, opening vaults, collecting treasures, and inserting map rocks. In order to open a map vault, you must grasp a map rock and place it in the proper hole.