Skip to main content

CURRENTLY SOLD OUT

Interaction Studies of Fexofenadine von Hina Shehnaz (2012, Taschenbuch)

About this product

About this product

Produktinformation

Fexofenadine is the major metabolite of terfenadine, but its pharmacokinetics differs from that of terfenadine, it is eliminated from the liver into bile in unchanged form. The aim of the present work is to study the availability of fexofenadine in presence of antacids, H2-receptor antagonists, quinolones, metformin hydrochloride. Owing to these interactions, metal complexes of fexofenadine were synthesized with various essential and trace elements like magnesium, calcium, chromium, manganese, iron, nickel, copper, zinc and cadmium. In order to study its structure activity relationship derivatives of fexofenadine were synthesized with various compounds. Metal complexes and synthesized compounds were characterized by their physical parameters and with spectroscopic techniques like AA, CHN, FT-IR, 1H-NMR, UV and mass spectra. The synthesized derivatives of fexofenadine were subjected to antihistaminic and anticholinergic activity studies on guinea pig ileum and compared with the reference drug. These compounds exhibited antihistaminic and spasmolytic activity but not anticholinergic activity observed from their EC50 values. All these activities were dose dependent in nature.

Produktkennzeichnungen

ISBN-10
3659154628
ISBN-13
9783659154621
eBay Product ID (ePID)
165789078

Produkt Hauptmerkmale

Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
308 Seiten
Verlag
Lap Lambert Academic Publishing
Publikationsname
Interaction Studies of Fexofenadine
Autor
Hina Shehnaz
Format
Taschenbuch
Erscheinungsjahr
2012

Zusätzliche Produkteigenschaften

Hörbuch
No
Inhaltsbeschreibung
Paperback
Item Length
22cm
Item Height
1cm
Item Width
15cm
Item Weight
475g

Best Selling in Textbooks

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Best Selling in Textbooks

Desk Reference to the Diagnostic Criteria from DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)
5.0 out of 5 stars based on 6 product ratings
$11.66 New
---- Used
PMBOK® Guide Ser.: Guide to the Project Management Body of Knowledge (PMBOK Guide) and the Standard for Project Management by Project Management Institute (2021, Trade Paperback)
4.9 out of 5 stars based on 7 product ratings
$18.79 New
$17.99 Used
Self Heal by Design : The Role of Micro-organisms for Health by Barbara O'Neill (2018, Trade Paperback)
5.0 out of 5 stars based on 14 product ratings
$34.99 New
---- Used
Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR by American Psychiatric Association (2022, Trade Paperback)
4.6 out of 5 stars based on 15 product ratings
$35.06 New
$32.99 Used
National Electrical Code 2023 by (NFPA) National Fire Protection Association (2022, Trade Paperback)
5.0 out of 5 stars based on 2 product ratings
$34.79 New
$29.99 Used
Cognitive Behavior Therapy : Basics and Beyond by Judith S. Beck (2020, Hardcover)
5.0 out of 5 stars based on 4 product ratings
$18.95 New
$17.66 Used
NFPA 70® Handbook with Tabs : 2023 Edition by National Fire Protection Association (NFPA) (2022, Hardcover)
No ratings or reviews yet
$58.99 New
$58.97 Used

Save on Textbooks

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- Save on Textbooks

Desk Reference to the Diagnostic Criteria from DSM-5-TR
$11.66
Trending at $13.18
PMBOK A Guide to the Project Management Body of Knowledge 7th edition (Pb) 📋
$17.99
Trending at $34.20
Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR Brand new
$32.00
Trending at $41.00
National Electrical Code 2023 Edition by National Fire Protection SPIRAL
$35.30
Trending at $40.50
Natural Remedies For All Kind of Disease Inspired by Barbara O'Neill's Teachings
$16.49
Trending at $17.93
The Pocket Guide to the DSM-5-TR Diagnostic Exam by Abraham M..........
$13.00
Trending at $13.28

You may also like

Current slide {CURRENT_SLIDE} of {TOTAL_SLIDES}- You may also like