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Epigenetics for Drug Discovery: Volume 48 Hardback Book The Fast Free Shipping
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eBay item number:305153860076
Item specifics
- Condition
- ISBN
- 1849738823
- EAN
- 9781849738828
- Release Title
- Epigenetics for Drug Discovery: Volume 48
- Artist
- various
- Brand
- N/A
- Colour
- N/A
- Book Title
- Epigenetics for Drug Discovery: Volume 48
- Publication Year
- 2015
- Series
- Issn Ser.
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Publication Name
- Epigenetics for Drug Discovery
- Item Length
- 9.2in
- Publisher
- Royal Society of Real Chemistry, T.H.E.
- Item Width
- 6.1in
- Item Weight
- 23 Oz
- Number of Pages
- 321 Pages
About this product
Product Information
Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number of biotechnology companies targeting epigenetic processes to treat diseases ranging from cancer to Huntington's disease and from inflammation to sickle cell anaemia. The book is structured in three main sections. The first section introduces epigenetics and explain its importance at both a phenomenological and molecular level. The second section goes on to review how each of the big breakthroughs in drug discovery in this field have developed, with a strong emphasis on case histories. The final section highlights the ongoing challenges in creating safe and efficacious epigenetic drugs. Written and edited by experts within the field from both industry and academia, this book provides an invaluable guide to this developing field for medicinal chemists working in academia and in the pharmaceutical industry.
Product Identifiers
Publisher
Royal Society of Real Chemistry, T.H.E.
ISBN-10
1849738823
ISBN-13
9781849738828
eBay Product ID (ePID)
212703887
Product Key Features
Publication Name
Epigenetics for Drug Discovery
Format
Hardcover
Language
English
Publication Year
2015
Series
Issn Ser.
Type
Textbook
Number of Pages
321 Pages
Dimensions
Item Length
9.2in
Item Width
6.1in
Item Weight
23 Oz
Additional Product Features
Series Volume Number
Volume 48
Lc Classification Number
Qh450
Reviews
This book provides a rather compact overview to the field which will be very useful to medicinal chemists who want to get a short introduction into the field but also biologists who want to learn about some general aspects of epigenetic drug discovery.
Table of Content
Epigenetics - What it is and Why it Matters; Enzyme and Protein Families that Regulate Histone Modifications and Crosstalk; Epigenetics and Disease; Targeting DNA Methylation; Targeting Histone Acetylation; Targeting Histone Lysine Methyltransferases in Cancer; Targeting Non-Acetylation Histone Erasers; Progress in Targeting Epigenetic Readers; Who will Bebefit from Epigenetic Drugs; Dosing - When Less Is More; Histone Methyltransferase Activity Assays; Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose?;
Copyright Date
2016
Topic
Life Sciences / Biochemistry, Life Sciences / Genetics & Genomics, Pharmacology, Life Sciences / Biology
Lccn
2015-458786
Intended Audience
Scholarly & Professional
Illustrated
Yes
Genre
Science, Medical
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- GB 922696893
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eBay item number:305153860076
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